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Because the goal is local gut exposure, the oral route is most often selected specifically when the gut is the target rather than as a substitute for systemic delivery

After dietary fiber intake, acetate is the most abundant microbiota-derived SCFAs in the blood and can quickly resolve MSU-induced inflammation by promoting caspase-dependent apoptosis of neutrophils and the excretion of the anti-inflammatory IL-10 against LPS-induced inflammation [31]

-glucans are glucose polymers that are generally obtained from the cell walls of yeast, such as Candida , Aspergillus , and Pneumocystis 117

53,54,55 Both the phosphorylation of PGD at Y481 upon EGFR activation and acetylation of PGD at K76 and K294 by acetyltransferases enhance its activation for producing NADPH in cancer cells